Entity Central Index Key
Cover [Abstract]
Document Type
Document Type
Amendment Flag
Amendment Flag
Document Period End Date
Document Period End Date
Document Fiscal Year Focus
Document Fiscal Year Focus
Document Fiscal Period Focus
Document Fiscal Period Focus
Trading Symbol
Trading Symbol
Entity Registrant Name
Entity Registrant Name
Entity Central Index Key
Current Fiscal Year End Date
Current Fiscal Year End Date
Entity Well-known Seasoned Issuer
Entity Well Known Seasoned Issuer
Entity Current Reporting Status
Entity Current Reporting Status
Entity Voluntary Filers
Entity Voluntary Filers
Entity Filer Category
Entity Filer Category
Entity Small Business
Entity Small Business
Entity Emerging Growth Company
Entity Emerging Growth Company
ICFR Auditor Attestation Flag
Icfr Auditor Attestation Flag
Entity Shell Company
Entity Shell Company
Entity Common Stock, Shares Outstanding
Entity Common Stock Shares Outstanding
Entity Public Float
Entity Public Float
Title of 12(b) Security
Security12b Title
Entity File Number
Entity File Number
Entity Incorporation, State or Country Code
Entity Incorporation State Country Code
Entity Tax Identification Number
Entity Tax Identification Number
Entity Interactive Data Current
Entity Interactive Data Current
Security Exchange Name
Security Exchange Name
Entity Address, Address Line One
Entity Address Address Line1
Entity Address, Address Line Two
Entity Address Address Line2
Entity Address, City or Town
Entity Address City Or Town
Entity Address, State or Province
Entity Address State Or Province
Entity Address, Postal Zip Code
Entity Address Postal Zip Code
City Area Code
City Area Code
Local Phone Number
Local Phone Number
Document Annual Report
Document Annual Report
Document Transition Report
Document Transition Report
Prepaid research and development noncurrent.
Statement Of Financial Position [Abstract]
Assets
Assets [Abstract]
Current assets:
Assets Current [Abstract]
Cash and cash equivalents
Cash And Cash Equivalents At Carrying Value
Short-term marketable securities
Available For Sale Securities Debt Securities Current
Prepaid expenses and other current assets
Prepaid Expense And Other Assets Current
Total current assets
Assets Current
Long-term marketable securities
Available For Sale Securities Debt Securities Noncurrent
Property and equipment, net
Property Plant And Equipment Net
Right of use asset - operating lease
Operating Lease Right Of Use Asset
Restricted cash
Restricted Cash Noncurrent
Prepaid research and development, net of current portion
Prepaid Research And Development Noncurrent
Other assets
Other Assets Noncurrent
Total assets
Assets
Liabilities and Stockholders' Equity
Liabilities And Stockholders Equity [Abstract]
Current liabilities:
Liabilities Current [Abstract]
Accounts payable
Accounts Payable Current
Accrued expenses
Accrued Liabilities Current
Deferred revenue
Contract With Customer Liability Current
Lease liability - operating lease
Operating Lease Liability Current
Finance lease obligations
Finance Lease Liability Current
Total current liabilities
Liabilities Current
Long-term liabilities:
Liabilities Noncurrent [Abstract]
Lease liability - operating lease, net of current portion
Operating Lease Liability Noncurrent
Finance lease obligations, net of current portion
Finance Lease Liability Noncurrent
Other long-term liabilities
Other Liabilities Noncurrent
Total long-term liabilities
Liabilities Noncurrent
Commitments and contingencies (Note 14)
Commitments And Contingencies
Stockholders' equity
Stockholders Equity [Abstract]
Common stock, $0.001 par value 250,000,000 shares authorized as of December 31, 2020 and December 31, 2019. 38,183,273 shares issued and outstanding as of December 31, 2020 and 32,266,814 shares issued and outstanding as of December 31, 2019.
Common Stock Value
Additional paid-in capital
Additional Paid In Capital Common Stock
Accumulated other comprehensive loss
Accumulated Other Comprehensive Income Loss Net Of Tax
Accumulated deficit
Retained Earnings Accumulated Deficit
Total stockholders' equity
Stockholders Equity
Total liabilities and stockholders' equity
Liabilities And Stockholders Equity
Common stock, par value
Common Stock Par Or Stated Value Per Share
Common stock, authorized
Common Stock Shares Authorized
Common stock, Issued
Common Stock Shares Issued
Common stock, outstanding
Common Stock Shares Outstanding
Income Statement [Abstract]
Revenue
Revenues
Operating expenses:
Operating Expenses [Abstract]
Research and development
Research And Development Expense
General and administrative
General And Administrative Expense
Total operating expenses
Operating Expenses
Loss from operations
Operating Income Loss
Other income (expense):
Nonoperating Income Expense [Abstract]
Interest and investment income
Investment Income Nonoperating
Interest expense
Interest Expense
Other expense
Other Nonoperating Income Expense
Other income (expense), net
Nonoperating Income Expense
Net loss
Net Income Loss
Net loss per share - basic and diluted
Earnings Per Share Basic And Diluted
Weighted-average common stock outstanding - basic and diluted
Weighted Average Number Of Share Outstanding Basic And Diluted
Comprehensive loss:
Comprehensive Income Net Of Tax [Abstract]
Net loss
Net unrealized (loss) gain on marketable securities
Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
Comprehensive loss
Comprehensive Income Net Of Tax
Statement Of Stockholders Equity [Abstract]
Statement [Table]
Statement [Table]
Accumulated Other Comprehensive Income (Loss)
Statement Equity Components [Axis]
Equity Component
Equity Component [Domain]
Common Stock $0.001 Par Value
Common Stock [Member]
Additional Paid-in Capital
Additional Paid In Capital [Member]
Accumulated Other Comprehensive Income (Loss)
Accumulated Other Comprehensive Income [Member]
Accumulated Deficit
Retained Earnings [Member]
Sale of Stock
Subsidiary Sale Of Stock [Axis]
Sale of Stock
Sale Of Stock Name Of Transaction [Domain]
At-the-market offering,
At-the-market Offering
At The Market Offering [Member]
Statement [Line Items]
Statement [Line Items]
Balance
Balance (in Shares)
Shares Outstanding
Proceeds from issuance of common stock, net of issuance costs
Stock Issued During Period Value New Issues
Proceeds from issuance of common stock, net of issuance costs, Shares
Stock Issued During Period Shares New Issues
Proceeds from issuance of pre-funded common stock warrants, net of issuance costs
Adjustments To Additional Paid In Capital Warrant Issued
Exercise of options
Stock Issued During Period Value Stock Options Exercised
Exercise of options, shares
Stock Issued During Period Shares Stock Options Exercised
Issuance of restricted stock
Stock Issued During Period Value Restricted Stock Award Gross
Issuance of restricted stock, shares
Stock Issued During Period Shares Restricted Stock Award Gross
Issuance of common stock under employee stock purchase plan
Stock Issued During Period Value Employee Stock Purchase Plan
Issuance of common stock under employee stock purchase plan, Shares
Stock Issued During Period Shares Employee Stock Purchase Plans
Cancellation of restricted stock
Stock Issued During Period Shares Restricted Stock Award Forfeited
Equity-based compensation expense
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
Unrealized gain (loss) on securities
Balance
Balance (in Shares)
Reduction in carrying amount of operating lease right-of-use asset.
Increase (decrease) in prepaid research and development net of current portion.
Increase Decrease in Operating Lease Liability.
Proceeds from employee stock purchases and exercise of stock options.
Noncash purchase of property, plant and equipment in accounts payable and accrued liabilities adjustments.
Assets acquired under operating lease obligation.
Issuance costs included in accounts payable and accrued expenses.
Noncash investing items.
Noncash financing items.
Statement Of Cash Flows [Abstract]
Cash flows from operating activities:
Net Cash Provided By Used In Operating Activities [Abstract]
Net loss
Profit Loss
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract]
Depreciation
Depreciation
Equity-based compensation expense
Share Based Compensation
Accretion/amortization of investment securities
Accretion Amortization Of Discounts And Premiums Investments
Reduction in carrying amount of operating lease right of use asset
Reduction In Carrying Amount Of Operating Lease Right Of Use Asset
Changes in operating assets and liabilities:
Increase Decrease In Operating Capital [Abstract]
Prepaid expenses and other current assets
Increase Decrease In Prepaid Deferred Expense And Other Assets
Prepaid research and development, net of current portion
Increase Decrease In Prepaid Research And Development Net Of Current Portion
Other assets
Increase Decrease In Other Operating Assets
Accounts payable and accrued expenses
Increase Decrease In Accounts Payable And Accrued Liabilities
Deferred revenue
Increase Decrease In Contract With Customer Liability
Operating lease liabilities
Increase Decrease In Operating Lease Liability
Other long-term liabilities
Increase Decrease In Other Noncurrent Liabilities
Net cash used in operating activities
Net Cash Provided By Used In Operating Activities
Cash flows from investing activities:
Net Cash Provided By Used In Investing Activities [Abstract]
Purchases of marketable securities
Payments To Acquire Available For Sale Securities Debt
Proceeds from maturity of marketable securities
Proceeds From Sale And Maturity Of Marketable Securities
Proceeds from redemption of marketable securities
Proceeds From Maturities Prepayments And Calls Of Available For Sale Securities
Purchases of property and equipment
Payments To Acquire Property Plant And Equipment
Net cash provided by investing activities
Net Cash Provided By Used In Investing Activities
Cash flows from financing activities:
Net Cash Provided By Used In Financing Activities [Abstract]
Payments on finance lease obligations
Finance Lease Principal Payments
Proceeds from issuance/sale of common stock, net of issuance costs
Proceeds From Issuance Of Common Stock
Proceeds from employee stock purchases and exercise of stock options
Proceeds From Employee Stock Purchases And Exercise Of Stock Options
Proceeds from sale of pre-funded warrants, net of issuance costs
Proceeds From Issuance Of Warrants
Net cash provided by financing activities
Net Cash Provided By Used In Financing Activities
Net increase in cash, cash equivalents and restricted cash
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
Cash, cash equivalents and restricted cash at beginning of period
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
Cash, cash equivalents and restricted cash at end of period
Supplemental disclosure of non-cash investing activities:
Noncash Investing Items [Abstract]
Property and equipment purchases included in accounts payable and accrued expenses
Noncash Purchase Of Property Plant And Equipment In Accounts Payable And Accrued Liabilities Adjustments
Assets acquired under operating lease obligation
Assets Acquired Under Operating Lease Obligation
Supplemental disclosure of non-cash financing activities:
Noncash Financing Items [Abstract]
Issuance costs included in accounts payable and accrued expenses
Issuance Costs Included In Accounts Payable And Accrued Expenses
Cash paid for interest
Interest Paid Net
Documents Incorporated by Reference
Documents Incorporated By Reference [Text Block]
Organization Consolidation And Presentation Of Financial Statements [Abstract]
Nature of Business
Organization Consolidation And Presentation Of Financial Statements Disclosure [Text Block]
Accounting Policies [Abstract]
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Fair Value Disclosures [Abstract]
Fair Value of Financial Instruments
Fair Value Disclosures [Text Block]
Available for sale securities disclosure.
Investments Debt And Equity Securities [Abstract]
Available-for-Sale Investments
Available For Sale Securities Disclosure [Text Block]
Prepaid expenses and other current assets.
Text Block [Abstract]
Prepaid Expenses and Other Current Assets
Prepaid Expenses And Other Current Assets [Text Block]
Property Plant And Equipment [Abstract]
Property and Equipment, Net
Property Plant And Equipment Disclosure [Text Block]
Payables And Accruals [Abstract]
Accrued Expenses
Accounts Payable Accrued Liabilities And Other Liabilities Disclosure Current [Text Block]
Equity [Abstract]
Common Stock
Stockholders Equity Note Disclosure [Text Block]
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Equity-based Compensation and Equity Incentive Plans
Disclosure Of Compensation Related Costs Share Based Payments [Text Block]
Collaboration Agreements
Collaborative Arrangement Disclosure [Text Block]
Earnings Per Share [Abstract]
Net Loss per Share
Earnings Per Share [Text Block]
Income Tax Disclosure [Abstract]
Income Taxes
Income Tax Disclosure [Text Block]
Leases [Abstract]
Leases
Leases Of Lessee Disclosure [Text Block]
Commitments And Contingencies Disclosure [Abstract]
Commitments and Contingencies
Commitments And Contingencies Disclosure [Text Block]
Compensation And Retirement Disclosure [Abstract]
Employee Benefits
Compensation And Employee Benefit Plans [Text Block]
Related Party Transactions [Abstract]
Related-Party Transactions
Related Party Transactions Disclosure [Text Block]
Quarterly Financial Information Disclosure [Abstract]
Selected Quarterly Data (Unaudited)
Quarterly Financial Information [Text Block]
Basis of Presentation
Basis Of Accounting Policy Policy [Text Block]
Principles of Consolidation
Consolidation Policy [Text Block]
Use of Estimates
Use Of Estimates
Cash Equivalents
Cash And Cash Equivalents Policy [Text Block]
Concentration of Credit Risk
Concentration Risk Credit Risk
Restricted Cash
Cash And Cash Equivalents Restricted Cash And Cash Equivalents Policy
Fair Value
Fair Value Measurement Policy Policy [Text Block]
Available-for-Sale Securities
Marketable Securities Policy
Property and Equipment
Property Plant And Equipment Policy [Text Block]
Impairment of Long-Lived Assets
Property Plant And Equipment Impairment
Leases
Lessee Leases Policy [Text Block]
Research and Development Costs
Research And Development Expense Policy
Revenue recognition
Revenue From Contract With Customer Policy [Text Block]
Equity-Based Compensation
Share Based Compensation Option And Incentive Plans Policy
Income Taxes
Income Tax Policy [Text Block]
Net Loss Per Share
Earnings Per Share Policy [Text Block]
Segment Information
Segment Reporting Policy Policy [Text Block]
New accounting pronouncements.
New Accounting Pronouncements
New Accounting Pronouncements Policy [Text Block]
Recently adopted accounting pronouncements.
Recently Adopted Accounting Pronouncements
Recently Adopted Accounting Pronouncements Policy [Text Block]
Recently Issued Accounting Pronouncements
New Accounting Pronouncements Policy Policy [Text Block]
Schedule of Reconciliation of Cash, Cash Equivalents, and Restricted Cash
Schedule Of Restricted Cash And Cash Equivalents [Text Block]
Tabular disclosure of the useful life of long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale.
Schedule of Useful Life of Property and Equipment
Schedule Of Property Plant And Equipment Useful Life Table [Text Block]
Schedule of Company's Classified Assets Measured at Fair Value on Recurring Basis
Schedule Of Fair Value Assets And Liabilities Measured On Recurring Basis Table [Text Block]
Summary of Available-for-Sale Securities Held
Schedule Of Available For Sale Securities Reconciliation Table [Text Block]
Schedule of prepaid expenses and other current assets.
Schedule of Prepaid Expenses and Other Current Assets
Schedule Of Prepaid Expenses And Other Current Assets Table [Text Block]
Schedule of Property and Equipment, Net
Property Plant And Equipment [Text Block]
Schedule of Accrued Expenses
Schedule Of Accrued Liabilities Table [Text Block]
Schedule of shares of common stock reserved for future issuance.
Schedule of Shares of Common Stock Reserved for Future Issuance
Schedule Of Shares Of Common Stock Reserved For Future Issuance Table [Text Block]
Plan Name
Plan Name [Axis]
Plan Name
Plan Name [Domain]
Long term incentive plan 2015 and 2017.
2015 and 2017 Plan
Long Term Incentive Plan2015 And2017 [Member]
Schedule of Weighted Average Assumption Used Black-Scholes Option-pricing Model for Stock Options Issued to Employees and Non-employees
Schedule Of Share Based Payment Award Stock Options Valuation Assumptions Table [Text Block]
Schedule of Stock Option Activity
Schedule Of Share Based Compensation Stock Options Activity Table [Text Block]
Schedule of Restricted Common Stock Activity
Nonvested Restricted Stock Shares Activity Table [Text Block]
Schedule of Equity-based Compensation Expenses
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Text Block]
Schedule of Equity-based Compensation Expenses by Award Type
Disclosure Of Share Based Compensation Arrangements By Share Based Payment Award [Text Block]
Schedule of Computation of Basic and Diluted Net Loss per Share
Schedule Of Earnings Per Share Basic And Diluted Table [Text Block]
Schedule of Potentially Common Shares Excluded from Calculation of Net Loss Per share
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block]
Schedule of Temporary Differences Between Basis of Deferred Tax Assets and Liabilities
Schedule Of Deferred Tax Assets And Liabilities Table [Text Block]
Reconciliation of Statutory Federal Income Tax Rate to Company's Effective Income Tax Rate
Schedule Of Effective Income Tax Rate Reconciliation Table [Text Block]
Schedule of Valuation Allowance
Summary Of Valuation Allowance [Text Block]
Components of Lease Cost for Operating Leases
Lease Cost Table [Text Block]
Lessee weighted average remaining lease term and weighted average discount rate.
Summary of Weighted Average Remaining Lease Term and Weighted Average Discount Rate for Operating Leases
Lessee Weighted Average Remaining Lease Term And Weighted Average Discount Rate Table [Text Block]
Lessee, operating and finance lease, liability, maturity.
Summary of Maturity of Lease Liabilities for Operating Leases
Lessee Operating And Finance Lease Liability Maturity Table [Text Block]
Selected Quarterly Data (unaudited)
Schedule Of Quarterly Financial Information Table [Text Block]
Cash, cash equivalents, and short-term marketable securities
Cash Cash Equivalents And Short Term Investments
Summary of significant accounting policies.
Summary of significant accounting policies.
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Credit Facility
Credit Facility [Axis]
Credit Facility
Credit Facility [Domain]
Letter of Credit
Letter Of Credit [Member]
Accounting Standards Update
Adjustments For New Accounting Pronouncements [Axis]
Accounting Standards Update
Type Of Adoption [Member]
ASU 2019-12
Accounting Standards Update201912 [Member]
ASU 2018-13
Accounting Standards Update201813 [Member]
ASU 2018-15
Accounting Standards Update201815 [Member]
ASU 2018-18
Accounting Standards Update201818 [Member]
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Cash equivalents maturity
Additional Cash And Cash Equivalent Related Text
Cash equivalents
Cash Equivalents At Carrying Value
Cash
Cash
Restricted cash included in other long-term assets
Cash Collateral For Borrowed Securities
Total cash, cash equivalents, and restricted cash shown in the consolidated statement of cash flows
Represents net transfers in and out of assets and liabilities measured at fair value on a recurring basis using Level 1, Level 2 and Level 3 inputs.
Transfers of assets and liabilities between Level 1, Level 2, or Level 3
Fair Value Asset Liability Transfers Between Level1 Level2 And Level3 Amount
Schedule Of Property Plant And Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Long-Lived Tangible Asset
Property Plant And Equipment By Type [Axis]
Long-Lived Tangible Asset
Property Plant And Equipment Type [Domain]
Computer and office equipment.
Computer and Office Equipment
Computer And Office Equipment [Member]
Furniture and Fixtures
Furniture And Fixtures [Member]
Laboratory Equipment
Equipment [Member]
Leasehold Improvements
Leasehold Improvements [Member]
Property Plant And Equipment [Line Items]
Property Plant And Equipment [Line Items]
Useful life
Property Plant And Equipment Useful Life
Useful life
Property Plant And Equipment Estimated Useful Lives
Impairment charge
Tangible Asset Impairment Charges
Lessee, operating lease, existence of option to extend
Lessee Operating Lease Existence Of Option To Extend
Lessee, operating lease, option to extend
Lessee Operating Lease Option To Extend
Revenue, practical expedient, incremental cost of obtaining contract [true/false]
Revenue Practical Expedient Incremental Cost Of Obtaining Contract
Revenue, practical expedient, remaining performance obligation, description
Revenue Practical Expedient Remaining Performance Obligation Description
Description of tax benefit likely to be realized upon settlement
Income Tax Examination Likelihood Of Unfavorable Settlement
Number of operating segment
Number Of Operating Segments
Change in accounting principle, accounting standards update, adopted [true false]
Change In Accounting Principle Accounting Standards Update Adopted
Change in accounting principle, accounting standards update, adoption date
Change In Accounting Principle Accounting Standards Update Adoption Date
Change in accounting principle, accounting standards update, immaterial effect [true false]
Change In Accounting Principle Accounting Standards Update Immaterial Effect
Fair Value Asset Measured On Recurring Basis [Line Items]
Fair Value Asset Measured On Recurring Basis [Table]
Fair Value Asset Measured On Recurring Basis [Table]
Fair Value Asset Measured On Recurring Basis [Table]
Measurement Frequency
Fair Value By Measurement Frequency [Axis]
Measurement Frequency
Fair Value Measurement Frequency [Domain]
Recurring
Fair Value Measurements Recurring [Member]
Fair Value Hierarchy and NAV
Fair Value By Fair Value Hierarchy Level [Axis]
Fair Value Hierarchy and NAV
Fair Value Measurements Fair Value Hierarchy [Domain]
Quoted Prices in Active Markets for Identical Assets (Level 1)
Fair Value Inputs Level1 [Member]
Significant Other Observable Inputs (Level 2)
Fair Value Inputs Level2 [Member]
Significant Unobservable Inputs (Level 3)
Fair Value Inputs Level3 [Member]
Financial Instrument
Financial Instrument [Axis]
Financial Instruments
Transfers And Servicing Of Financial Instruments Types Of Financial Instruments [Domain]
Corporate debt securities
Corporate Debt Securities [Member]
Investment Type
Investment Type [Axis]
Investments
Investment Type Categorization [Member]
Commercial paper
Commercial Paper [Member]
US treasury and government long-term debt securities.
U.S. Government Agency Securities and Treasuries
U S Treasury And Government Long Term Debt Securities [Member]
Cash and Cash Equivalents
Cash And Cash Equivalents [Axis]
Cash and Cash Equivalents
Restricted Cash And Cash Equivalents Cash And Cash Equivalents [Member]
Money market funds
Money Market Funds [Member]
Fair Value Asset Measured On Recurring Basis [Line Items]
Fair Value Asset Measured On Recurring Basis [Line Items]
Cash and Cash Equivalents
Cash And Cash Equivalents Fair Value Disclosure
Short-term investments
Investments Fair Value Disclosure
Total assets
Assets Fair Value Disclosure
Marketable securities
Marketable Securities
Debt Securities Available For Sale [Table]
Debt Securities Available For Sale [Table]
U.S. government agency securities
U S Government Agencies Debt Securities [Member]
Schedule of Available-for-sale Securities [Line Items]
Schedule Of Available For Sale Securities [Line Items]
Amortized cost
Available For Sale Debt Securities Amortized Cost Basis
Gross unrealized gains
Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
Gross unrealized losses
Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
Fair Value
Available For Sale Securities Debt Securities
Other than temporary impairment losses investments number debt securities available for sale.
Number of investments in unrealized loss position
Debt Securities Available For Sale Unrealized Loss Position Number Of Positions
Number of investments in unrealized loss position, more than twelve months
Debt Securities Available For Sale Continuous Unrealized Loss Position12 Months Or Longer Number Of Positions
Aggregate fair value of securities in unrealized loss position
Debt Securities Available For Sale Unrealized Loss Position
Number of securities with other than temporary impairment
Other Than Temporary Impairment Losses Investments Number Debt Securities Available For Sale
Prepaid research and development, current.
Deferred Costs Capitalized Prepaid And Other Assets Disclosure [Abstract]
Prepaid insurance
Prepaid Insurance
Prepaid research and development
Prepaid Research And Development Current
Other prepaid expenses
Other Prepaid Expense Current
Other current assets
Other Assets Current
Total
Depreciation expense
Construction in Progress
Construction In Progress [Member]
Property and equipment, gross
Property Plant And Equipment Gross
Less accumulated depreciation
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
Property and equipment, net
Accrued research and development, current.
Payroll related
Employee Related Liabilities Current
Professional fees
Accrued Professional Fees Current
Research and development
Accrued Research And Development Current
Other
Other Accrued Liabilities Current
Total accrued expenses
Stockholders Equity Note [Abstract]
Schedule Of Stock By Class [Table]
Schedule Of Stock By Class [Table]
Common Stock
Related Party
Related Party Transactions By Related Party [Axis]
Related Party
Related Party [Domain]
Ginkgo Bioworks, Inc.
Ginkgo Bioworks, Inc.
Ginkgo Bioworks Inc [Member]
Class of Warrant or Right
Class Of Warrant Or Right [Axis]
Class of Warrant or Right
Class Of Warrant Or Right [Domain]
Pre-Funded Warrants.
Pre-Funded Warrants
Pre Funded Warrants [Member]
Statistical Measurement
Range [Axis]
Statistical Measurement
Range [Member]
Maximum
Maximum [Member]
Minimum [Member]
Minimum [Member]
at the market.
ATM
At The Market [Member]
Subsequent Event Type
Subsequent Event Type [Axis]
Subsequent Event Type
Subsequent Event Type [Domain]
Subsequent Event
Subsequent Event [Member]
Cowen and company LLC.
Cowen and Company, LLC
Cowen And Company L L C [Member]
Class Of Stock [Line Items]
Class Of Stock [Line Items]
Number of votes entitled to each share of common stock.
Number of votes entitled to each share of common stock
Number Of Votes Entitled To Each Share Of Common Stock
Cash dividends
Dividends Common Stock Cash
Sale of common stock and prefunded warrant price per share.
Class of warrant or right exercise price of warrants paid at closing of offering.
Proceeds from issuance of common stock and pre funded warrants.
Warrants exercised.
Sale of common stock, shares
Sale of stock, price per share
Sale Of Common Stock And Prefunded Warrant Price Per Share
Warrants to purchase shares of common stock
Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights
Warrants exercise price per share
Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1
Warrants exercise price per share paid at closing of offering
Class Of Warrant Or Right Exercise Price Of Warrants Paid At Closing Of Offering
Proceeds, net of issuance costs, from issuance of common stock and pre-funded warrants
Proceeds From Issuance Of Common Stock And Pre Funded Warrants
Proceeds from sale of common stock, net of issuance costs
Warrants exercised
Warrants Exercised
Unbeneficial percentage of ownership after exercise of common stock outstanding effect to issuance.
Unbeneficial percentage of ownership after exercise of common stock outstanding effect to issuance
Unbeneficial Percentage Of Ownership After Exercise Of Common Stock Outstanding Effect To Issuance
Common Stock Issuable Under Pre-Funded Warrants
Option Indexed to Issuer's Equity
Option Indexed To Issuers Equity Equity [Axis]
Option Indexed to Issuer's Equity, Type
Option Indexed To Issuers Equity Type [Domain]
Options To Purchase Common Stock
Employee Stock Option [Member]
Employee Stock Purchase Plan
Employee Stock [Member]
Total Shares of Common Stock Reserved for Future Issuance
Common Stock Capital Shares Reserved For Future Issuance
Share based compensation arrangement by share based payment award percentage of shares outstanding.
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Long Term Incentive Plan 2015.
Plan 2015
Long Term Incentive Plan2015 [Member]
ESPP
Award Type
Award Type [Axis]
Award Type
Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain]
Restricted Common Stock
Restricted Stock [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Percentage of shares outstanding
Share Based Compensation Arrangement By Share Based Payment Award Percentage Of Shares Outstanding
Percentage of discount for employees under ESPP
Share Based Compensation Arrangement By Share Based Payment Award Discount From Market Price Offering Date
Purchase price as a percentage of fair value under ESPP
Sharebased Compensation Arrangement By Sharebased Payment Award Purchase Price Of Common Stock Percent
Share-based compensation arrangement by share-based payment award, options outstanding, weighted average exercise price, and additional disclosures.
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price And Additional Disclosures [Abstract]
Title of Individual
Title Of Individual [Axis]
Title of Individual
Title Of Individual With Relationship To Entity [Domain]
Employees and nonemployees.
Employees and Nonemployees
Employees And Nonemployees [Member]
Expected term
Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
Weighted-average, risk-free interest rate
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
Expected volatility
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
Dividend yield
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
Outstanding Beginning balance, Number of options
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
Granted, Number of options
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
Exercised, Number of options
Cancelled/Forfeited, Number of options
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
Outstanding Ending balance, Number of options
Number of options, Vested or expected to vest
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number
Number of options, Exercisable
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
Beginning balance, Weighted-average price
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
Granted, Weighted-average price
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
Exercised, Weighted-average price
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
Cancelled/Forfeited, Weighted-average price
Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
Ending balance, Weighted-average price
Weighted-average price Vested or expected to vest
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Exercise Price
Weighted-average price, Exercisable
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
Outstanding, weighted average remaining contractual term (Year)
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
Weighted average remaining contractual term, Vested or expected to vest
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Remaining Contractual Term1
Weighted average remaining contractual term, Exercisable
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
Share based compensation arrangement by share based payment award options grants in period intrinsic value.
Share based compensation arrangement by share based payment award options forfeitures and expirations in period intrinsic value.
Beginning balance, Aggregate Intrinsic
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
Granted, Aggregate Intrinsic value
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Intrinsic Value
Exercised, Aggregate Intrinsic value
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
Cancelled/Forfeited, Aggregate Intrinsic value
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures And Expirations In Period Intrinsic Value
Ending balance, Aggregate Intrinsic value
Aggregate Intrinsic value, Vested or expected to vest at December 31, 2020
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Aggregate Intrinsic Value
Aggregate Intrinsic value, Exercisable at December 31, 2020
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
Share based compensation by share based arrangement award, options available for aggregate intrinsic value.
Number of options in money
Share Based Compensation By Share Based Arrangement Award Options Available For Aggregate Intrinsic Value
Weighted average grant date fair value per share of options granted to employees
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
Total fair value of awards vested
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Total Fair Value
Employee unrecognized compensation expense
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Stock Options
Employee unrecognized compensation cost, period of recognition
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1
Granted
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period
Beginning balance, Number of unvested shares/units
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
Granted, Number of shares/units
Vested, Number of shares/units
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period
Forfeited, Number of shares/units
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeited In Period
Ending balance, Number of unvested shares/units
Beginning balance, Unvested Grant date fair value
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
Granted, Grant date fair value
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value
Vested, Grant date fair value
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Weighted Average Grant Date Fair Value
Forfeited, Grant date fair value
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeitures Weighted Average Grant Date Fair Value
Ending balance, Unvested Grant date fair value
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Income Statement Location
Income Statement Location [Axis]
Income Statement Location
Income Statement Location [Domain]
Research and Development Expense
Research And Development Expense [Member]
General and Administrative Expense
General And Administrative Expense [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Equity-based compensation expense
Allocated Share Based Compensation Expense
Stock Options
Restricted Stock Awards
Prepayment to related party for collaboration agreement.
Related party transaction collaboration agreement, initial term.
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Collaborative Arrangement and Arrangement Other than Collaborative
Type Of Arrangement [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Arrangements And Nonarrangement Transactions [Member]
Ginkgo Collaboration
Abb Vie agreement.
Abb Vie Agreement
Abb Vie Agreement [Member]
Business Acquisition
Business Acquisition [Axis]
Business Acquisition, Acquiree
Business Acquisition Acquiree [Domain]
IBDCo [Member]
Ibdco
Ibdco [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Number of shares sold
Current pre-paid research and development
Prepaid Expense Current
Non-current pre-paid research and development
Prepaid Expense Noncurrent
Prepayment to related party for collaboration agreement
Prepayment To Related Party For Collaboration Agreement
Related party transaction collaboration agreement, initial term
Related Party Transaction Collaboration Agreement Initial Term
Anticipated completion period for research and development projects.
Collaboration in research and development
Anticipated Completion Of Research And Development Projects Period
Recognition of revenue
Current deferred revenue
Earnings Per Share Reconciliation [Abstract]
Numerator:
Net Income Loss Available To Common Stockholders Diluted [Abstract]
Net loss
Denominator:
Weighted Average Number Of Shares Outstanding [Abstract]
Weighted-average common shares outstanding - basic and diluted
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Antidilutive Securities
Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis]
Antidilutive Securities, Name
Antidilutive Securities Name [Domain]
Unvested Restricted Stock Awards [Member]
Unvested Restricted Common Stock Awards
Unvested Restricted Stock Awards [Member]
Potential Shares Issuable Under ESPP
Stock Compensation Plan [Member]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Potentially Common Shares Excluded from Calculation of Net Loss Per share
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
Income tax disclosure.
Income tax disclosure.
Income Tax Disclosure [Table]
Income Tax Disclosure [Table]
Income Tax Authority
Income Tax Authority [Axis]
Income Tax Authority
Income Tax Authority [Domain]
State
State And Local Jurisdiction [Member]
Income Tax Authority, Name
Income Tax Authority Name [Axis]
Income Tax Authority, Name
Income Tax Authority Name [Domain]
Federal
Internal Revenue Service I R S [Member]
Tax Credit Carryforward
Tax Credit Carryforward [Axis]
Tax Credit Carryforward, Name
Tax Credit Carryforward Name [Domain]
Research and Development.
Research [Member]
Income Tax Disclosure [Line Items]
Income Tax Disclosure [Line Items]
Income tax benefits for the net operating losses
Income Tax Expense Benefit
Deferred tax assets other long-term liabilities.
Deferred tax assets lease liabilities.
Deferred tax liabilities, right of use assets.
Deferred tax assets:
Deferred Tax Assets Net [Abstract]
Net operating loss carryforwards
Deferred Tax Assets Operating Loss Carryforwards
Tax credit carryforwards
Deferred Tax Assets Tax Credit Carryforwards
Accrued expenses
Deferred Tax Assets Tax Deferred Expense Reserves And Accruals Accrued Liabilities
Property and equipment
Deferred Tax Assets Property Plant And Equipment
Other long-term liabilities
Deferred Tax Assets Other Long Term Liabilities
Lease liabilities
Deferred Tax Assets Lease Liabilities
Equity compensation
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost
Amortizable intangibles
Deferred Tax Assets Goodwill And Intangible Assets
Other
Deferred Tax Assets Other
Gross deferred tax assets
Deferred Tax Assets Gross
Deferred tax liabilities:
Deferred Tax Liabilities Net [Abstract]
Property and equipment
Deferred Tax Liabilities Property Plant And Equipment
Right of use assets
Deferred Tax Liabilities Right Of Use Assets
Gross deferred tax liabilities
Deferred Income Tax Liabilities
Valuation allowance
Deferred Tax Assets Valuation Allowance
Net deferred tax assets
Deferred Tax Assets Liabilities Net
Valuation allowance
U.S. federal statutory rate
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
State income taxes, net of federal benefit, Tax Rate
Effective Income Tax Rate Reconciliation State And Local Income Taxes
Other permanent differences, Tax Rate
Effective Income Tax Rate Reconciliation Nondeductible Expense Other
Tax credits, Tax Rate
Effective Income Tax Rate Reconciliation Tax Credits
Other items, Tax Rate
Effective Income Tax Rate Reconciliation Other Adjustments
Net change in valuation allowance, Tax Rate
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
Effective income tax rate
Effective Income Tax Rate Continuing Operations
Balance at beginning of year
Increase in valuation allowance
Valuation Allowance Deferred Tax Asset Change In Amount
Balance at end of year
Operating loss carryforwards expiration year.
Operating loss carryforwards subject to expiration.
Operating loss carryforwards not subject to expiration.
Net operating loss carryforwards
Operating Loss Carryforwards
Net operating loss carryforwards subject to expiration
Operating Loss Carryforwards Subject To Expiration
Net operating loss carryforwards not subject to expiration
Operating Loss Carryforwards Not Subject To Expiration
Net operating loss carryforwards expiration year
Operating Loss Carryforwards Expiration Year
Tax credit carryforwards
Tax Credit Carryforward Amount
Unrecognized tax benefits
Unrecognized Tax Benefits
Income tax examination description
Income Tax Examination Description
Interest or penalties accrued
Income Tax Examination Penalties And Interest Accrued
Rentable Space Under Lease Agreement
Operating leases rent expense annual rental payments.
The amount the lessee agrees to invest into a tenant improvement of a leased property.
Lessee Lease Description [Table]
Lessee Lease Description [Table]
Master contract services agreement.
Master Services Agreement
Master Contract Services Agreement [Member]
Legal Entity
Legal Entity [Axis]
Entity
Entity [Domain]
Azzur Group Limited Liability Company.
Azzur Group, LLC
Azzur Group Limited Liability Company [Member]
Lessee Lease Description [Line Items]
Lessee Lease Description [Line Items]
Laboratory and office space to be leased
Rentable Space Under Lease Agreement
Operating lease annual rent
Operating Leases Rent Expense Annual Rental Payments
Term of lease
Lessee Operating Lease Term Of Contract
Tenant improvement investment
Tenant Improvement Investment Obligation
Letter of credit
Line Of Credit Facility Maximum Borrowing Capacity
Renewal term of lease
Lessee Operating Lease Renewal Term
Lessee, operating lease, existence of option to terminate
Lessee Operating Lease Existence Of Option To Terminate
Access and Use of space under agreement.
Term of agreement.
Agreement expiration date.
Estimated expenses to be incurred in access and use of space under agreement.
Access and use of space under agreement
Access And Use Of Space Under Agreement
Term of agreement
Term Of Agreement
Agreement expiration date
Agreement Expiration Date
Estimated expenses to be incurred
Estimated Expenses To Be Incurred In Access And Use Of Space Under Agreement
Cash paid included in operating cash flows
Operating Lease Payments
Operating and variable lease cost.
Operating lease cost.
Operating leases
Operating Lease Cost [Abstract]
Operating lease cost
Operating Lease Cost
Short-term lease cost
Short Term Lease Cost
Variable lease cost
Variable Lease Cost
Operating and variable lease cost
Operating And Variable Lease Cost
Operating Lease, Weighted average discount rate
Operating Lease Weighted Average Discount Rate Percent
Operating Lease, Weighted average remaining lease term (years)
Operating Lease Weighted Average Remaining Lease Term1
Operating Leases
Operating Lease Liabilities Payments Due [Abstract]
2021
Lessee Operating Lease Liability Payments Due Next Twelve Months
2022
Lessee Operating Lease Liability Payments Due Year Two
2023
Lessee Operating Lease Liability Payments Due Year Three
2024
Lessee Operating Lease Liability Payments Due Year Four
2025
Lessee Operating Lease Liability Payments Due Year Five
Thereafter
Lessee Operating Lease Liability Payments Due After Year Five
Total lease payments
Lessee Operating Lease Liability Payments Due
Less: imputed interest
Lessee Operating Lease Liability Undiscounted Excess Amount
Total lease liabilities
Operating Lease Liability
Current lease liabilities
Long-term lease liabilities
Eligible employees to contribute to 401(k) plan
Defined Contribution Plan Employer Matching Contribution Percent Of Match
Employee contribution
Defined Contribution Plan Maximum Annual Contributions Per Employee Percent
Maximum matching contributions as a percentage of eligible compensation
Defined Contribution Plan Employer Matching Contribution Percent
Schedule Of Related Party Transactions By Related Party [Table]
Schedule Of Related Party Transactions By Related Party [Table]
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Current Pre-Paid Research and Development.
Non Current Pre-Paid Research and Development
Prepaid research and development expenses.
Prepayment to related party for collaboration agreement
Related party transaction collaboration agreement, initial term
Current Pre-Paid Research and Development
Current Pre Paid Research And Development
Non Current Pre-Paid Research and Development
Non Current Pre Paid Research And Development
Prepaid research and development expenses
Prepaid Research And Development Expenses
Operating expenses
Loss from operations