Synlogic, Inc.
301 Binney St., Suite 402
Cambridge, Massachusetts 02142
September 26, 2023
VIA EDGAR
U.S. Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549
Attention: Cindy Polynice
| Re: | Synlogic, Inc. |
| Registration Statement on Form S-1 |
| File No. 333-274421 |
| Request for Acceleration |
Dear Ms. Polynice:
Pursuant to Rule 461 of Regulation C promulgated under the Securities Act of 1933, as amended, Synlogic, Inc. (the “Registrant”) hereby requests acceleration of the effective date of its Registration Statement on Form S-1 (File No. 333-274421), so that it may become effective at 5:00 p.m. (Washington, D.C. time) on September 28, 2023, or as soon thereafter as practicable.
Please call Daniel A. Bagliebter or Nishant M. Dharia of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C., counsel to the Registrant, at (212) 692-6856 or (212) 692-8174 with any comments or questions regarding this matter.
| Very truly yours,
Synlogic, Inc. | ||
| By: | /s/ Aoife Brennan MB, BCh, BAO, MMSc | |
| Name: Aoife Brennan MB, BCh, BAO, MMSc | ||
| Title: President and Chief Executive Officer | ||
| cc: | Synlogic, Inc. |
| Brendan St. Amant |
| Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. |
| Daniel A. Bagliebter, Esq. |
| Nishant M. Dharia, Esq. |