SYNLOGIC, INC.
301 Binney Street, Suite 402
Cambridge, Massachusetts 02142
July 29, 2021
VIA EDGAR
U.S. Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549
Attention: Ms. Abby Adams
| Re: | Synlogic, Inc. |
Registration Statement on Form S-3
Filed July 23, 2021
File No. 333- 258151 (the “Registration Statement”)
Acceleration Request
Ladies and Gentlemen:
In accordance with Rule 461 of Regulation C promulgated under the Securities Act of 1933, as amended, Synlogic, Inc. (the “Registrant”) hereby respectfully requests that the Securities and Exchange Commission accelerate the effective date of the above-referenced Registration Statement to Friday, July 30, 2021, at 4:01 p.m., Eastern Time, or as soon as thereafter practicable.
The cooperation of the staff in meeting the timetable described above is very much appreciated.
Please contact Daniel A. Bagliebter of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C., counsel to the Registrant, at (212) 692-6856 with any questions regarding this request.
| Very truly yours, |
| SYNLOGIC, INC. |
| /s/ Gregg Beloff |
| Gregg Beloff Interim Chief Financial Officer |
| cc: | Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. |
Matthew J. Gardella, Esq.
Daniel A. Bagliebter, Esq.